Griffin Chure, PhD

Curriculum Vitae

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Ph.D. Biochemistry & Molecular Biophysics, California Institute of Technology, 2020

  • Dissertation Topic: The Molecular Biophysics of Adaptation in Transcriptional Regulation
  • Dissertation Adviser: Prof. Rob Phillips

B.Sc. Biology & B.Sc. Chemistry — University of Utah, 2013

  • Thesis Topic: The Biochemical Assembly of the Bacterial Flagellar Motor
  • Thesis Adviser: Prof. David F. Blair


indicates equal contribution

Forthcoming Publications and Preprints

  1. Griffin Chure, Avi Flamholz, Nicholas S. Sarai, Tine Valencic, Yinon Bar-On,Ron Milo, and Rob Phillips (2020). "Human Impacts by the Numbers". Manuscript in preparation.

  2. Nathan M. Belliveau ☭ , Griffin Chure☭, Christina L. Heuschen, Hernan G. Garcia,Jane Kondev, Daniel S. Fisher, Julie A. Theriot, and Rob Phillips (2020). "Fundamental Limits on the Rate of Bacterial Growth" Manuscript in preparation.

  3. Griffin Chure, Zofii A. Kaczmarek, and Rob Phillips (2019). "Physiological Adaptability and Parametric Versatility in a Simple Genetic Circuit." Preprint on bioRxiv. doi: 10.1101/2019.12.19.878462. Website GitHub Repository

Peer-reviewed Publications

  1. Manuel Razo-Mejia, Sarah Marzen, Griffin Chure, Muir Morrison, Rachel Taubman, and Rob Phillips. (2020). "First-principles prediction of the information processing capacity of a simple genetic circuit". Physical Review E. 102 DOI: 10.1103/PhysRevE.102.022404( Open Access PDF GitHub Repository Website

  2. Kathrin S. Laxhuber, Muir Morrison, Griffin Chure, Nathan M. Belliveau, Charlotte Strandkvist, Kyle L. Naughton, and Rob Phillips (2020). "Theoretical investigation of a genetic switch for metabolic adaptation". PLoS ONE 15 (2020). DOI:10.1371/journal.pone.0226453. Open Access PDF

  3. Soichi Hirokawa, Griffin Chure, Nathan M. Belliveau, Geoffrey A. Lovely, Michael Anaya, David G. Schatz, David Baltimore, and Rob Phillips (2020). Sequence-Dependent Dynamics of Endogenous and Synthetic RSSs in V(D)J Recombination, Nucleic Acids Research 48(12). DOI: 10.1093/nar/gkaa418. Open Access PDF GitHub Repository Website

  4. Griffin Chure, Manuel Razo-Mejia, Nathan M. Belliveau, Tal Einav, Zofii A. Kaczmarek, Stephanie L. Barnes, Mitchell Lewis, and Rob Phillips (2019). Predictive Shifts In Free Energy Couple Mutations To Their Phenotypic Consequences. *PNAS* 116. DOI: 10.1073/pnas.1907869116. Open Access PDF GitHub Repository Website

  5. Rob Phillips, Nathan M. Belliveau, Griffin Chure, Hernan G. Garcia, Manuel Razo-Mejia, and Clarissa Scholes (2019). Figure 1 Theory Meets Figure 2 Experiments in the Study of Gene Expression. Annual Reviews of Biophysics 48. DOI: 10.1146/annurev-biophys-052118-115525. PDF From Publisher

  6. Griffin Chure ☭, Heun Jin Lee ☭, Akiko Rasmussen, and Rob Phillips (2018). Connecting the Dots Between Mechanosensitive Channel Abundance, Osmotic Shock, and Survival At Single-Cell Resolution, Journal of Bacteriology 200. DOI: 10.1128/JB.00460-18. Open Access PDF GitHub Repository Website

  7. Manuel Razo-Mejia ☭, Stephanie L. Barnes ☭, Nathan M. Belliveau ☭, Griffin Chure ☭, Tal Einav ☭, Mitchell Lewis, and Rob Phillips (2018). Tuning Transcriptional Regulation Through Signaling: A Predictive Theory of Allosteric Induction, Cell Systems 6. DOI: 10.1016/j.cels.2018.02.004. Open Access PDF GitHub Repository Website

Doctoral Thesis

  1. Griffin Chure (2020). The Molecular Biophysics of Evolutionary and Physiological Adaptation. California Institute of Technology. DOI:10.7907/q8h6-xr92. Open Access PDF GitHub Repository Website Version